pentobarbital will lower the level or impact of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.Take into consideration expanding dosages as needed of drugs which happen to be CYP2B6 and CYP3A substrates and lowering dosages as necessary of drugs which are CYP2C19 substrates.Potential for pentobarbi